Mesoporation is a technique for the transdermally delivery of cosmetics that sees the synergy between electroporation of tissues and electrical stimulation. Through the provision of a parameterized waveform, the mesoporation promotes the creation of families of electropores, with consequent increase in the permeability of the skin, subsequently conveys the cosmetic in depth for electrodiffusion through the new paths generated in the intra and extra-cellular phase of electroporation . Thanks to Mesoporation has the advantage of conveying in depth even large molecules in the various layers of the skin.